Acute Breast Sepsis

Suspected Breast Infection



Acute breast sepsis should be referred to the surgical admitting team e.g if systemically unwell, obvious abscess, or necrotic/compromised skin.

Clinical presentation of mastitis includes skin erythema, tenderness, firm and/or indurated tissue.


Initial Primary Care Management

  • Lactational - High dose Flucloxacillin  (or Clarithromycin if penicillin allergic) for 10-14 days
  • Non lactational - Augmentin (or Clarithromycin AND metronidazole if penicillin allergic) for 10-14 days

Review at 48 hours

  • If improving, complete course
  • If deteriorating, refer to the surgical admitting team.


Refer to the symptomatic breast clinic if:

  • Resolution of symptoms is slow or symptoms are recurrent
  • Patient over 50 years (alongside initiating treatment)



Date Reviewed                              November 2021

Next Review Date                          November 2022

Author                                            Dr I Boyd, RMS GP Sifter

Reviewed By                                  Dr M Attridge, RMS GP Sifter

Contributor                                     Dr Rebecca Osborne, GPwSI Breast, RCHT



Version No.  3.0