Raised Vitamin B12

 

Do not measure B12 levels in those on parenteral replacement – it will be high

 

Causes

Oral self-administration of supra-physiological doses

Liver disease, renal failure, autoimmune disease (SLE, RA), inflammatory disorders and malignancy

 It can be associated with myeloproliferative disorders but these can effectively be excluded if there is a normal Full Blood Count and Blood Film

 

Contributors:

Dr Richard Noble, Consultant Haematologist, RCHT

Dr Bridgitte Wesson, GP&Kernow RMS Haematology guideline lead

Review date: 13/07/2020

Next Review: 13/07/2021