Anaphylaxis
www.nice.org.uk/guidance/CG134
A severe allergic reaction with airway and/or breathing and/or circulation problems.
Causes:
- Food (commonest cause in children)
- Latex
- Exercise (ask if wheat or fish eaten just prior to exercise, as very rarely can be food – induced exercise anaphylaxis)
- Drugs (no need to refer if single drug and alternative available eg penicillin allergy)
- Venom induced (most commonly bee or wasp)
Refer all cases of anaphylaxis to Paediatric Allergy Clinic
Adrenaline Auto – Injectors:
There is good BSACI guidance on who should receive these at www.BSACI.org
In most cases where provoking allergen may be accidentally encountered again (or idiopathic), prescribe 2 adrenaline autoinjector when referring, due to small risk of recurrence in intervening wait for appointment.
Use the excellent information sheet at https://www.medicinesforchildren.org.uk/medicines/adrenaline-auto-injector-for-anaphylaxis/
Demonstrate with 'dummy' pen if available
Doses (BNFc)
If child < 15kg discuss with Allergy Consultant before prescribing
If < 30kg prescribe 0.15 mg
If > 30kg prescribe 0.3mg (if Epipen, can switch to 0.3mg dose of same pen if > 26kg)
Date: February 2025
Review Date: February 2027
Specialty Lead GP: Dr M Schick, RMS
Authors: Simon Bedwani, Consultant Paediatrician, RCHT
Dr S Burns GP RMS