Actinic (Solar) Keratosis
Introduction
AK should routinely be managed in primary care.
Although less than 1/1000 AKs progress to SCC per annum, a patient with an average of 7 Aks has a 10% risk of one transforming in the next 10 years1.
In Scope:
- Actinic Keratosis
Not In Scope:
- Skin Cancer
Red Flags
- Rapidly growing lesions
- Firm lesions with fleshy base and or are painful
- Have thick scale (grade III AK)
*This list is not exhaustive
Primary Care Management
AK-Pathway-2025-Update-web.pdf
Important to stress skin cancer prevention to patient to prevent new lesions/SCC. E.G. Wearing high factor SPF.
Treatment of actinic keratosis does not result in reduction of progression to SCC2 but it will help highlight those not responding to normal therapy.
Advice and Guidance
Available via e-RS
Investigations
Diagnosis is usually clinical. No investigations required.
Referral
1.Fast track cancer pathway
- Any concerns regarding skin malignancy
2.Dermatology routine referral: (For consideration of Photodynamic Therapy (PDT))
- Young patients (<35 years)
- Evidence of extensive UV damage
- Immunosuppressed
- Periocular AK
- Xeroderma pigmentosum
- Failure to respond to primary care management
Useful Information:
Professional:
Patient:
- Actinic (solar) keratosis– Patient Leaflet
- 5-fluorouracil cream
- Imiquimod cream
- Sunscreen and sun safety - NHS
References:
- AK-Pathway-2025-Update-web.pdf
- Berker, D., McGregor, J., Mohd Mustapa, M.F., Exton, L.S., & Hughes, B.R. (2017). British Association of Dermatologists’ guidelines for the care of patients with actinic keratosis 2017. British Journal of Dermatology, 176
Page Review Information
Review Date: 21 April 2026
Next Review date: 21 April 2028
Sifter Name: Dr Kate Northridge
Contributor: Dr Alexander Anderson, Consultant Dermatologist Royal Cornwall Hospital Trust